Alfuzosin hydrochloride

Research use only, not for human use.

Alfuzosin hydrochloride is an?α1 adrenergic receptor?antagonist used to treat benign prostatic hyperplasia (BPH).

Alfuzosin hydrochloride is an?α1 adrenergic receptor?antagonist used to treat benign prostatic hyperplasia (BPH).(In Vivo):Alfuzosin hydrochloride (10 mg/kg, p.o.; single) potently antagonizes phenylephrine-induced increases in urethral and arterial pressures up to 6 hours post dosing.

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Alfuzosin hydrochloride (10 mg/kg, p.o.; single) potently antagonizes phenylephrine-induced increases in urethral and arterial pressures up to 6 hours post dosing. Animal Model:Male Wistar rats (250-450 g).Dosage:10 mg/kg Administration:Oral administration; single.Result:Increased prostatic concentrations to 4.1-8.6 times higher than plasma concentration.

SL 77499-10 | Uroxatral

Endocrinology/Hormones

Adrenergic Receptor

α-adrenergic receptor

Endocrinology

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81403-68-1

425.91

C19H27N5O4·HCl

>98% (HPLC)

Ethanol: 85 mg/mL (199.57 mM); Water: 85 mg/mL (199.57 mM); DMSO: 85 mg/mL (199.57 mM)

Cl.COC1=C(OC)C=C2C(N)=NC(=NC2=C1)N(C)CCCNC(=O)C1CCCO1

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(-20℃)

With Ice Pack

≥ 2 years